Laboratory of Bioprocess Engineering

About LEB


The Laboratory of Bioprocess Engineering develops projects in the area of enzymatic technology: biocatalysis, new technologies and methodologies for immobilization of enzymes, biotechnological treatment of effluents.

E-mail: leb@itp.org.br

Phone number: +55 79 3218 2190 Telephone extension 2632



Coordination

Dra. Alini Tinoco Fricks
Lattes


Researchers



Students

Gabrielle Souza da Silva - Doctorate Student
Lucas Costa Lopes - Doctorate Student
Micael Nunes Melo - Doctorate Student
Milson dos Santos Barbosa - Doctorate Student
Rachel Freire Boaventura - Doctorate Student
Sílvia Regina Soares Marquez - Doctorate Student
Glaucia Nicolau dos Santos - Master Student
Ianny Andrade - Master Student
Jéssica Jéssi Carvalho de Melo - Master Student
Kennedy Costa da Conceição - Master Student
Tamara Stella Mendonça Azevedo - Master Student
Thiara Santana Gomes - Master Student


Scientific production

Article -

MARTINS, SÍLVIA RS; DOS SANTOS, AMANDA; Fricks, Aline T.; LIMA, ÁLVARO S; MATTEDI, SILVANA; SILVA, DANIEL P; SOARES, CLEIDE MF; CABRERA-PADILLA, REBECA Y. Protic ionic liquids influence on immobilization of Lipase Burkholderia cepacia on hybrid supports. JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY, v. 92, p. 633-641.


Article -

ALMEIDA, LAYS C.; BARBOSA, ANDERSON S.; Fricks, Alini T.; FREITAS, LISIANE S.; Lima, Álvaro S.; SOARES, CLEIDE M.F.. Use of conventional or non-conventional treatments of biochar for lipase immobilization. PROCESS BIOCHEMISTRY, v. 61, p. 124-129.


Article -

LUCENA, I. V.; BRANDAO, I. V.; MATTEDI, S. ; SOUZA, R. L. ; SOARES, C. M. F. ; FRICKS, A. T.; LIMA, A. S. . Use of protic ionic liquids as adjuvants in PEG-based ATPS for the purification of radish peroxidase. FLUID PHASE EQUILIBRIA, v. 452, p. 1-8.


Article -

PLÁCIDO, N. S. O.; CARLOS, A. L. S.; MATTEDI, SILVANA; SOARES, C. M. F.; FRICKS, A. T.; LIMA, A. S.. Ionic Liquid-Based Ultrasonic-Assisted Extraction of Alkaloids from Cacao (Theobroma cacao). CHEMICAL ENGINEERING TRANSACTIONS, v. 64, p. 49-54.


Article -

QUEIROZ, M. L. B.; CONCEICAO, K. C.; MELO, M. N.; SÁNCHEZ, OSMAR CALDERÓN; Alvarez, H. M.; SOARES, C. M. F.; FRICKS, A. T.. IMOBILIZAÇÃO DE PEROXIDASE DE RAIZ FORTE EM BAGAÇO DE CANA-DE-AÇÚCAR. QUÍMICA NOVA, v. 41, p. 1019-1024.


Article -

LOPES, LUCAS COSTA; BRANDÃO, IGOR VENTURA; SÁNCHEZ, OSMAR CALDERÓN; FRANCESCHI, ELTON; BORGES, GUSTAVO; Dariva, Cláudio; Fricks, Alini Tinoco. Horseradish peroxidase biocatalytic reaction monitoring using Near-Infrared (NIR) Spectroscopy. PROCESS BIOCHEMISTRY, v. 71, p. 127-133.


Article -

PLÁCIDO, NILMARA S.O. ; CARLOS, ANDRÉ L.S. ; GALVÃO, JOSEPH U.S. ; Souza, Ranyere L. ; SOARES, CLEIDE M.F. ; MATTEDI, SILVANA ; Fricks, Alini T. ; Lima, Álvaro S. . Protic ionic liquids as a constituent of biphasic systems based on acetonitrile: Phase diagram and alkaloid partitioning. SEPARATION AND PURIFICATION TECHNOLOGY, v. 200, p. 318-326.


Article -

FRICKS, A. T.; OESTREICHER, E. G.; Filho, Lucio Cardozo; FEIHRMANN, A. C.; CORDEIRO, Y.; DARIVA, C.; ANTUNES, O. A. C. Effects of compressed fluids on the activity and structure of horseradish peroxidase. The Journal of Supercritical Fluids, v. 50, p. 162-168.


Article -

Fricks, Alini Tinoco; Dariva, Cláudio; Alvarez, Heiddy Marquez; Santos, Alexandre Ferreira; Fortuny, Montserrat; Queiroz, Monna Lisa Barreto; Antunes, O.A.C. Compressed propane as a new and fast method of pre-purification of radish (Raphanus sativus L.) peroxidase. The Journal of Supercritical Fluids, v. 54, p. 153-158.


Article -

Barbosa, José Murillo P.; Souza, Ranyere L.; Fricks, Alini T.; Zanin, Gisella Maria; Soares, Cleide Mara F.; Lima, Álvaro S. Purification of lipase produced by a new source of Bacillus in submerged fermentation using an aqueous two-phase system. Journal of Chromatography. B (Print), v. 879, p. 3853-3858.


Article -

Barbosa, José Murillo P.; Souza, Ranyere L.; MELO, CLÁUDIA MOURA DE; Fricks, Alini T.; Soares, Cleide Mara F.; Lima, Álvaro S. Biochemical characterisation of lipase from a new strain of Bacillus sp. ITP-001. Química Nova (Impresso), v. 35, p. 1173-1178.


Article -

QUEIROZ, M. L. B.; Alvarez, H. M.; BOAVENTURA, R. F.; CARVALHO, N. B.; SOARES, C. M. F.; LIMA, A. S.; HEREDIA, M. F.; DARIVA, C.; FRICKS, A. T. Effect of the presence of surfactant and ionic liquids on the esterification of oleic acid catalyzed by immobilized lipase. African Journal of Biotechnology, v. 11, p. 16718-16724.


Article -

SOUZA, R. L.; RESENDE, W. C. S.; BARAO, C. E.; ZANIN, G. M.; CASTRO, H. F.; SANTOS, O. A. A.; FRICKS, A. T.; LIMA, A. S.; SOARES, C. M. F. Influence of the use of Aliquat 336 in the immobilization procedure in sol-gel of lipase from Bacillus sp. ITP - 001. Journal of Molecular Catalysis. B, Enzymatic (Print), v. 82, p. 1-16.


Article -

PADILLA, R. Y. C.; LISBOA, M. C.; FRICKS, A. T.; FRANCESCHI, E.; LIMA, A. S.; SILVA, D. P.; SOARES, C. M. F. Immobilization of Candida rugosa lipase on poly(3-hydroxybutyrate-co-hydroxyvalerate): a new eco-friendly support. Journal of Industrial Microbiology & Biotechnology, v. 39, p. 289-298. Citações:14|10


Article -

CABRERA-PADILLA, REBECA Y.; ALBUQUERQUE, MATHEUS; FIGUEIREDO, RENAN T.; Fricks, Alini T.; FRANCESCHI, ELTON; Lima, Álvaro S.; A DOS SANTOS, ONELIA A.; SILVA, DANIEL P.; SOARES, CLEIDE M. F. Immobilization and characterisation of a lipase from a new source, Bacillus sp. ITP-001. Bioprocess and Biosystems Engineering (Print), v. 36, p. 1385-1394.


Article -

DE BRITO CARDOSO, GUSTAVO; MOURÃO, TERESA; PEREIRA, FERNANDA MENEZES; FREIRE, MARA G.; Fricks, Alini Tinoco; SOARES, CLEIDE MARA FARIA; LIMA, ÁLVARO SILVA. Aqueous two-phase systems based on acetonitrile and carbohydrates and their application to the extraction of vanillin. Separation and Purification Technology (Print), v. 104, p. 106-11313.


Article -

CARVALHO, N. B.; BARBOSA, J. M. P.; Oliveira, M. V. S.; FRICKS, A. T.; LIMA, A. S.; SOARES, C. M. F. Biochemical properties of Bacillus sp. ITP-001 lipase immobilized with a sol gel process. Química Nova (Impresso), v. 36, p. 52-58.


Article -

BARBOSA, A. S.; SILVA, M. A. O.; CARVALHO, N. B.; MATTEDI, S.; IGLESIAS, M. A.; FRICKS, A. T.; LIMA, A. S.; FRANCESCHI, E.; SOARES, C. M. F. IMMOBILIZATION OF LIPASE BY ENCAPSULATION IN SILICA AEROGEL. Química Nova (Impresso), p. 969-976.


Article -

Souza, Ranyere L.; FARIA, EMANUELLE L. P.; FIGUEIREDO, RENAN T.; Fricks, Alini T.; ZANIN, GISELLA M.; SANTOS, ONÉLIA A. A.; Lima, Álvaro S.; SOARES, CLEIDE M. F.. Use of polyethylene glycol in the process of sol-gel encapsulation of Burkholderia cepacia lipase. Journal of Thermal Analysis and Calorimetry, v. 117, p. 301-306.


Article -

CARVALHO, N. B.; OLIVEIRA, M. A. S.; FRICKS, A. T.; FRANCESCHI, ELTON; DARIVA, C.; LIMA, A. S.; SOARES, C. M. F. Evaluation of activity of Bacillus lipase (free and immobilized) treated with compressed propane. Journal of Molecular Catalysis. B, Enzymatic (Print), v. 99, p. 130-135.


Article -

CABRERA-PADILLA, REBECA Y.; MELO, E. B.; PEREIRA, M. M.; FIGUEIREDO, R. T.; FRICKS, A. T.; FRANCESCHI, E.; LIMA, A. S.; SILVA, D. P.; SOARES, C. M. F. Use of ionic liquids as additives for the immobilization of lipase from. Journal of Chemical Technology and Biotechnology (1986), v. 90, p. 1308-1316.


Article -

CABRERA-PADILLA, REBECA Y.; LISBOA, MILENA C.; PEREIRA, MATHEUS M.; FIGUEIREDO, RENAN T.; FRANCESCHI, ELTON; Fricks, Alini T.; Lima, Álvaro S.; SILVA, DANIEL P.; SOARES, CLEIDE M. F. Immobilization of Candida rugosa lipase onto an eco-friendly support in the presence of ionic liquid. Bioprocess and Biosystems Engineering (Print), v. 38, p. 805-814.


Article -

MELO, M. N.; LOPES, L. C.; DARIVA, C.; GIRARDI, J. S.; LUCCHESE, A. M.; Alvarez, H. M.; FRICKS, A. T. Bioepoxidation of isosafrol catalyzed by radish and turnip peroxidases. African Journal of Biotechnology, v. 14, p. 1074-1080.


Article -

QUEIROZ, M. L. B.; BOAVENTURA, R. F.; MELO, M. N.; Alvarez, H. M.; SOARES, C. M. F.; LIMA, A. S.; HEREDIA, M. F.; DARIVA, C.; FRICKS, A. T. MICROWAVE ACTIVATION OF IMMOBILIZED LIPASE FOR TRANSESTERIFICATION OF VEGETABLE OILS. Química Nova (Impresso), v. 38, p. 303-308.


Article -

LOPES, L. C.; BARRETO, M. T. M.; GONCALVES, K. M.; Alvarez, H. M.; HEREDIA, M. F.; SOUZA, R. O. M. A.; CORDEIRO, Y.; DARIVA, C.; FRICKS, A. T.. Stability and Structural Changes of Horseradish Peroxidase: Microwave versus Conventional Heating Treatment. Enzyme and Microbial Technology, v. 69, p. 10-18.


Article -

MARTINS, S.; SANTOS, A.; FRICKS, A. T.; LIMA, A. S.; MATTEDI, S.; SILVA, D. P.; SOARES, C. M. F.; CABRERA-PADILLA, REBECA Y.. Protic ionic liquids influence on immobilization of Lipase on hybrid supports. Journal of Chemical Technology and Biotechnology (1986), v. 92, p. 633-641.


Article -

BARBOSA, A. S.; LISBOA, J. A.; Silva, M.A.O.; CARVALHO, N. B.; PEREIRA, M. M.; FRICKS, A. T.; MATTEDI, S.; LIMA, A. S.; FRANCESCHI, E.; SOARES, C. M. F.. THE NOVEL MESOPOROUS SILICA AEROGEL MODIFIED WITH PROTIC IONIC LIQUID FOR LIPASE IMMOBILIZATION. Química Nova (Impresso), p. 415.